LAB-IN-THE-LOOP

Close the loop between in silico tools and the wet lab bench. Helix can trigger at key points in the pipeline assays in your LIMS/ELN and will wait to ingest results, assess them and then continue automatically—with full traceability and governance.

Transform your lab operations

Helix turns lab work into a first-class step in your pipeline. It creates assay / synthesis / purchase requests in your LIMS/ELN, pauses at that gate, and resumes the pipeline the moment results arrive—feeding data back into models and next actions.

01
Create a re-usable lab integration step

Easily create agents to add to the Helix toolbelt that interact with your LIMS/ELN, usually to invoke a template or process. Common example is passing a protein of interest and ligands to be screened against it.

02
Auto-generate the request

Helix sends the work package to your LIMS/ELN with relevant metadata and attachments and assigns to a workflow.

03
Wait state 

The pipeline pauses and and awaits results.  

04
Result ingestion & QC

Helix ingests result files. Common to follow lab steps with either AI/ML/Stats assessment of the results and/or human review step to decide what goes forward.

05
Continue the pipeline

Filtered results feed ranking, filters, models, and next actions in the Helix pipeline. The run remains fully auditable from start to finish.

From screening to selections: a seamless workflow
The HTS → IC50 Workflow Example
  • Helix identifies dozens of interesting compounds purely in silico, but needs real world assessment
  • It creates an assay request in your LIMS/ELN 
  • Waits while plates run; zero polling scripts or manual file drops
  • Ingests IC50 results and merges them with all prior in-silico context
  • Auto-resumes the pipeline: re-ranks candidates and triggers follow-ups
Why This Matters

In silico is become incredibly able to automate R&D work, but we still need wet lab work to confirm and assess the in silico results.  Also, since all data captured in Helix and accessible at any time across all pipelines, this data can  also feed back into new models to make them more capable.

The moment data lands from your assay, Helix orchestrates the complete workflow for you seamless managing the purely computation with the real world leading to your discovery timeline accelerating dramatically with each automated pipeline.

The agentic operating system for life‑sciences discovery.

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