Helix: AI-Powered Drug Discovery Platform for Modern R&D Teams

Accelerate your drug discovery pipeline with Helix- the unified platform that connects in silico tools, wet lab operations, and scientific expertise through automated, traceable workflows.

Out-of-the-Box Tools—Ready to Run

Helix unifies hundreds of essential tools and data sources into the Helix Toolbelt, transforming them into intelligent, auditable agents that eliminate integration headaches and accelerate discovery workflows.

There are countless scientific tools and data sources available today, and the trend is more of these including powerful open source tools. There are also commercial tools and in-house tooling as well. Helix brings these together within a single, coordinated environment where every tool operates as a managed agent, with standardized data mapping, traceability, and support for humans and labs in the loop.

Helix exists to be the operating system for modern R&D, so you can rapidly leverage both new and existing agents and focus on the science instead of disconnected systems and data silos.

Small/Large Molecule Tools

Access industry-standard toolkits like RDKit, DeepChem, and DiffDock alongside commercial engines like Schrödinger Glide*. Perform PAINS filtering, similarity searches in ZINC, and molecular enumeration within unified, agent-driven workflows.

*Commercial tools require customer licenses.
Generative & Design

Leverage cutting-edge AI with NVIDIA NIMs (MolMIM), REINVENT, and EVO2 for novel molecule generation. Optimize compound libraries with sophisticated multi-parameter optimization (MPO) algorithms.

Biologics

Streamline antibody and protein engineering with codon optimization, sequence triage via IG-BLAST/VDJ, developability assessments, and specialized agents like RPocket for protein-specific workflows.

Bring Your In-House Tools
Helix Makes Them First-Class

Your proprietary methods and models represent significant intellectual capital. Helix honors that investment by making it easy to transform your custom and commercial tools into intelligent agents—fully integrated, traceable, and ready to run within your discovery workflows.

Rapid Integration

Wrap in-house models and commercial engines in hours, not weeks—then run them at scale with full traceability. Helix has already agentized industry standards like Schrödinger Glide, so just bring your license and it’s ready to add to your Helix toolbelt.

Flexible Implementation

Integrate using Helix’s lightweight agent-wrapping framework, with specifications that typically take less than a day to implement. The flexible architecture ensures any internal model or utility can become a first-class, orchestrated component within Helix.

Enterprise-Grade Deployment

Manage your agents through controlled draft and production lifecycle states using Helix’s built-in versioning. Once deployed, agents execute in scalable, in silico pipelines with live progress updates and full data traceability.

The agentic operating system for life‑sciences discovery.

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